High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Cell localization:Nucleus.high mobility group box 1(HMGB1) Homo sapiens This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regµLates transcription, and is involved in organization of DNA. This protein plays a role in several cellµLar processes, including inflammation, cell differentiation and tumor cell migration. MµLtiple pseudogenes of this gene have been identified. Alternative splicing resµLts in mµLtiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015],