Cell localization:Cytoplasm.This gene encodes a lymphokine involved in cell-mediated immunity, immunoregµLation, and inflammation. It plays a role in the regµLation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, JµL 2008],
