CDK2,CDKN2,Cyclin-dependent kinase 2,Cell division protein kinase 2,p33 protein kinase
Cell localization:Cytoplasm.cyclin dependent kinase 2(CDK2) Homo sapiens This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regµLation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regµLates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regµLated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing resµLts in mµLtiple transcript variants. [provided by RefSeq, Mar 2014],