CDC37,CDC37A,Hsp90 co-chaperone Cdc37,Hsp90 chaperone protein kinase-targeting subunit,p50Cdc37
Cell localization:Cytoplasm.The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecµLar chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, JµL 2008],
