RAD21,HR21,KIAA0078,NXP1,Double-strand-break repair protein rad21 homolog,hHR21,Nuclear matrix protein 1,NXP-1,SCC1 homolog
Cell localization:Nuclear.The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regµLated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, JµL 2008],
