PKB,RAC,PRKBA,PKB-ALPHA,RAC-ALPHA, AKT1 , AKT2, AKT3, Akt1/2/3, pan Akt,,AKT
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1.
