Enables gated channel activity, phospholipid scramblase activity, and protein homodimerization activity. Involved in several processes, including bleb assembly, inorganic ion transmembrane transport, and positive regulation of transport. Acts upstream of or within several processes, including bone mineralization involved in bone maturation, calcium activated phospholipid scrambling, and dendritic cell chemotaxis. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system, nervous system, respiratory system, sensory organ, and viscerocranium. Human ortholog(s) of this gene implicated in Scott syndrome, ankylosing spondylitis, and inflammatory bowel disease. Orthologous to human ANO6 (anoctamin 6). [provided by Alliance of Genome Resources, Apr 2022]