ALKBH5 Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE87757
Artikelname: ALKBH5 Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE87757
Hersteller Artikelnummer: AMRe87757
Alternativnummer: EKL-AMRE87757-50UL,EKL-AMRE87757-100UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Human, Mouse, Rat
Konjugation: Unconjugated
Alternative Synonym: ABH5, OFOXD, OFOXD1
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N6-methyladenosine in single-stranded DNA (in vitro) (PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).
Klonalität: Monoclonal
Molekulargewicht: Calculated MW:44 kDa, Observed MW:44-48 kDa
NCBI: 54890
UniProt: Q6P6C2
Puffer: Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Reinheit: Affinity Purification
Formulierung: Liquid
Target-Kategorie: ALKBH5
Application Verdünnung: WB 1:500-1:2000,IHC 1:200-1:2000