Cardiac Troponin I Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE87800
Hersteller Artikelnummer:
AMRe87800
Alternativnummer:
EKL-AMRE87800-50UL,EKL-AMRE87800-100UL
Hersteller:
EnkiLife
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FC, IHC, IP, WB
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Alternative Synonym:
CMH7, RCM1, cTnI, CMD2A, TNNC1, CMD1FF
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
