Human UltraPro Mutant CD19 Protein (CD1-HM129)
Artikelnummer:
KAB-CD1-HM129
- Bilder (10)
| Artikelname: | Human UltraPro Mutant CD19 Protein (CD1-HM129) |
| Artikelnummer: | KAB-CD1-HM129 |
| Hersteller Artikelnummer: | CD1-HM129 |
| Alternativnummer: | KAB-CD1-HM129-100UG, KAB-CD1-HM129-500UG |
| Hersteller: | KactusBio |
| Kategorie: | Proteine/Peptide |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | CD19, B4, CVID3, Leu-12, MGC12802 |
| Recombinant Human UltraPro Mutant CD19 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Pro20-Pro278 with site mutations. |
| Molekulargewicht: | The protein has a predicted MW of 29.93 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result. |
| Tag: | C-His |
| UniProt: | P15391 |
| Puffer: | Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Expression System: | HEK293 |
| Reinheit: | > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC |
| Formulierung: | Lyophilized |
| Sequenz: | Pro20-Pro278 with site mutations |
| Target-Kategorie: | CD19 |
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Immobilized Human UltraPro Mutant CD19, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for FMC63, mFc Tag with the EC50 of 9.5ng/ml determined by ELISA. |
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Immobilized Human UltraPro Mutant CD19, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA. |
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Immobilized Human UltraPro Mutant CD19, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Denintuzumab, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA. |
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Immobilized Human UltraPro Mutant CD19, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Inebilizumab, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA. |
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The purity of Human UltraPro Mutant CD19 is greater than 95% as determined by SEC-HPLC. |
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Human UltraPro Mutant CD19 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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Loaded Coltuximab on ProA-Biosensor can bind Human UltraPro Mutant CD19, His Tag with an affinity constant of 9.48 nM as determined in BLI assay (Gator Prime). |
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Loaded FMC63 on MFC-Biosensor can bind Human UltraPro Mutant CD19, His Tag with an affinity constant of 3.80 nM as determined in BLI assay (Gator Prime). |
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Loaded Inebilizumab on ProA-Biosensor can bind Human UltraPro Mutant CD19, His Tag with an affinity constant of 3.97 nM as determined in BLI assay (Gator Prime). |
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Loaded Denintuzumab on ProA-Biosensor can bind Human UltraPro Mutant CD19, His Tag with an affinity constant of 8.05 nM as determined in BLI assay (Gator Prime). |
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