Human TIGIT Protein (TIG-HM110)
Artikelnummer:
KAB-TIG-HM110
- Bilder (6)
| Artikelname: | Human TIGIT Protein (TIG-HM110) |
| Artikelnummer: | KAB-TIG-HM110 |
| Hersteller Artikelnummer: | TIG-HM110 |
| Alternativnummer: | KAB-TIG-HM110-100UG, KAB-TIG-HM110-500UG |
| Hersteller: | KactusBio |
| Kategorie: | Proteine/Peptide |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | TIGIT, VSIG9, VSTM3, WUCAM |
| Recombinant Human TIGIT Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Met22-Pro141. |
| Molekulargewicht: | The protein has a predicted MW of 14 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Bis-Tris PAGE result. |
| Tag: | C-His |
| UniProt: | Q495A1 |
| Puffer: | Lyophilized from 0.22µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Expression System: | HEK293 |
| Reinheit: | > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC |
| Formulierung: | Lyophilized |
| Sequenz: | Met22-Pro141 |
| Target-Kategorie: | TIGIT |
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Human TIGIT on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Human TIGIT is greater than 95% as determined by SEC-HPLC. |
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Human CD155, hFc Tag captured on Protein A chip, can bind Human TIGIT, His Tag with an affinity constant of 0.17uM as determined in a SPR assay (Biacore T200). |
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Serial dilutions of Anti-TIGIT Antibody were added into Human TIGIT, His Tag : Biotinylated CD155, hFc Tag binding reactioins. The half maximal inhibitiory concentration (IC50) is 0.46ug/ml. |
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Immobilized Human TIGIT, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-TIGIT Antibody, hFc Tag with the EC50 of 8.3ng/ml determined by ELISA. |
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Immobilized Human TIGIT, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human CD155, hFc Tag with the EC50 of 0.38ug/ml determined by ELISA. |
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