Trimetrexate (Standard), CAS [[52128-35-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-10373R
Hersteller Artikelnummer:
HY-10373R
Alternativnummer:
MCE-HY-10373R-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
CI-898 (Standard)
Trimetrexate (Standard) is the analytical standard of Trimetrexate (HY-10373). This product is intended for research and analytical applications. Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer[1][2][3][4][5].
