Carcinoembryonic Antigen (CEA) / CD66e Antibody, Rabbit, Polyclonal

Artikelnummer: NBT-1048-RBP21-P1
Artikelname: Carcinoembryonic Antigen (CEA) / CD66e Antibody, Rabbit, Polyclonal
Artikelnummer: NBT-1048-RBP21-P1
Hersteller Artikelnummer: 1048-RBP21-P1
Alternativnummer: NBT-1048-RBP21-P1-100
Hersteller: NeoBiotechnologies
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Purified native human CEA protein
Alternative Synonym: Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1)
This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
Klonalität: Polyclonal
Molekulargewicht: 80-200kDa
NCBI: 1048
UniProt: P06731
Formulierung: 200ug/ml of Ab purified from Rabbit Serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human colon carcinoma stained with CEA Rabbit Polyclonal Antibody.
Formalin-fixed, paraffin-embedded human colon carcinoma stained with CEA Rabbit Polyclonal Antibody.