Recombinant Crystallin Alpha B / CRYAB (Marker of Metaplastic Carcinoma) Antibody, IgG1, Clone: [rG2JF], Mouse, Monoclonal
Artikelnummer:
NBT-1410-MSM23-P1
Hersteller Artikelnummer:
1410-MSM23-P1
Alternativnummer:
NBT-1410-MSM23-P1-100
Hersteller:
NeoBiotechnologies
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC, WB
Spezies Reaktivität:
Human
Immunogen:
Synthetic peptide hemocyanin conjugate. The peptide corresponds to human alpha B crystallin amino acids 1 to 10.
Alternative Synonym:
AACRYA, Alpha B crystallin, Alpha-crystallin B chain, CRYA2, CTTP2, Heat shock 20 kD like protein, Heat shock protein beta-5, HspB5, Renal carcinoma antigen NY REN 27, Rosenthal fiber component
Alpha B crystallin is a lens protein which has some homology with the small heat shock proteins. It is expressed in tissues such as skeletal muscle, cardiac muscle, smooth muscle, renal tubular epithelium, Schwann cells, glial cells, thyroid epithelium, colonic epithelium and stratified squamous epithelium. Alpha B crystallin is also reported to be found in ubiquitinated intermediate filament inclusion bodies, such as Lewy bodies (neurofilaments), Rosenthal fibres (glial filaments) and Mallory bodies (cytokeratins). Alpha B crystallin is rarely found in neurofibrillary tangles. The role of Alpha B crystallin in these inclusion bodies is unknown, however, it may function as an accessory protein for intermediate filament aggregation.
200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified Recombinant Alpha B-crystallin Mouse Monoclonal Antibody (rG2JF). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human kidney stained with Recombinant Alpha B-crystallin Mouse Monoclonal Antibody (rG2JF). Inset: PBS instead of primary antibody, secondary only negative control.
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