IgA Secretory Component / ECM1 Antibody, IgG1, Clone: [SC05], Mouse, Monoclonal

Artikelnummer: NBT-1893-MSM1-P0
Artikelname: IgA Secretory Component / ECM1 Antibody, IgG1, Clone: [SC05], Mouse, Monoclonal
Artikelnummer: NBT-1893-MSM1-P0
Hersteller Artikelnummer: 1893-MSM1-P0
Alternativnummer: NBT-1893-MSM1-P0-20,NBT-1893-MSM1-P0-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: FC, IF, IHC
Spezies Reaktivität: Human, Rat
Immunogen: Full length native protein (purified) corresponding to Human IgA Secretory Component. Affinity-purified secretory component from human colostrum.
Alternative Synonym: ECM1, Extracellular Matrix Protein 1, Secretory Component p85, URBWD
This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.
Klonalität: Monoclonal
Klon-Bezeichnung: [SC05]
Molekulargewicht: ~80kDa
Isotyp: IgG1
NCBI: 1893
UniProt: Q16610
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Anwendungsbeschreibung: Flow Cytometry (0.5-1ug/million cells), Immunofluorescence (1-2ug/ml), ,Immunohistochemistry (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-2
Formalin-fixed, paraffin-embedded human colon carcinoma stained with Secretory Component Mouse Monoclonal Antibody (SC-05).
SDS-PAGE Analysis of Purified Secretory Component Mouse Monoclonal Antibody (SC-05). Confirmation of Purity and Integrity of Antibody.