Secretory Component protein isolated from human colostrum
Alternative Synonym:
ECM1, Extracellular Matrix Protein 1, Secretory Component p85, URBWD
This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human colon carcinoma stained with Secretory Component Mouse Monoclonal Antibody (SPM217).
SDS-PAGE Analysis of Purified Secretory Component Mouse Monoclonal Antibody (SPM217). Confirmation of Purity and Integrity of Antibody.
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