Fibronectin (Fibrin/Heparin-Binding Domain) Antibody, IgG2a, Clone: [616], Mouse, Monoclonal

Artikelnummer: NBT-2335-MSM5-P1
Artikelname: Fibronectin (Fibrin/Heparin-Binding Domain) Antibody, IgG2a, Clone: [616], Mouse, Monoclonal
Artikelnummer: NBT-2335-MSM5-P1
Hersteller Artikelnummer: 2335-MSM5-P1
Alternativnummer: NBT-2335-MSM5-P1-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: FC, IF, IHC
Spezies Reaktivität: Human, Porcine
Immunogen: High molecular weight proteins secreted by cultivated human fibroblasts
Alternative Synonym: Cold insoluble globulin (CIG), FINC, FN1, FNZ, GFND, GFND2, LETS, Migration stimulating factor (MSF), Ugl-Y3
Fibronectins are disulfide-linked, dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 29kDa N-terminal fibrin- and heparin-binding domain of fibronectin. It does not cross-react with MMP-2, MMP-9, or TIMP-2. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors.
Klonalität: Monoclonal
Klon-Bezeichnung: [616]
Molekulargewicht: 220kDa (monomer), 440kDa (dimer)
Isotyp: IgG2a
NCBI: 2335
UniProt: P02751
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Fibronectin Mouse Monoclonal Antibody (616).
SDS-PAGE Analysis of Purified Fibronectin Mouse Monoclonal Antibody (616). Confirmation of Purity and Integrity of Antibody.