CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on 95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
200ug/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human Hodgkin&apos,s Lymphoma stained with CD15 Mouse Monoclonal Antibody (MY-1).
Immunofluorescence staining of U937 cells using CD15 Mouse Monoclonal Antibody (MY-1) followed by goat anti-mouse IgG conjugated to CF488 (green). Nuclei are stained with Reddot.
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