GCHFR Antibody, IgG2, Clone: [GCHFR/7734], Mouse, Monoclonal

Artikelnummer: NBT-2644-MSM4-P1ABX
Artikelname: GCHFR Antibody, IgG2, Clone: [GCHFR/7734], Mouse, Monoclonal
Artikelnummer: NBT-2644-MSM4-P1ABX
Hersteller Artikelnummer: 2644-MSM4-P1ABX
Alternativnummer: NBT-2644-MSM4-P1ABX-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant fragment human GCHFR protein (exact sequence is proprietary)
Alternative Synonym: GTP Cyclohydrolase I Feedback Regulatory Protein, GTP Cyclohydrolase I Feedback Regulator, GFRP, p35
GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. Cross-linking experiments have shown that GFRP is usually expressed as a homodimer or pentamer.
Klonalität: Monoclonal
Klon-Bezeichnung: [GCHFR/7734]
Molekulargewicht: 63kDa
Isotyp: IgG2
NCBI: 2644
UniProt: P30047
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western blot analysis of SK-BR3 cell lysate using GCHFR Mouse Monoclonal Antibody (GCHFR/7734).
Formalin-fixed, paraffin-embedded human liver stained with GCHFR Mouse Monoclonal Antibody (GCHFR/7734). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.