Blood Group Antigen H Type 2 (CD173) Antibody, IgM, Clone: [19-OLE], Mouse, Monoclonal
Artikelnummer:
NBT-28-MSM1-P0
Hersteller Artikelnummer:
28-MSM1-P0
Alternativnummer:
NBT-28-MSM1-P0-20,NBT-28-MSM1-P0-100
Hersteller:
NeoBiotechnologies
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IF, IHC
Spezies Reaktivität:
Human
Immunogen:
Mucinous colonic adenocarcinoma
Alternative Synonym:
A transferase, ABO, B transferase, CD173, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, Histo-blood group A transferase, Histo-blood group B transferase, NAGAT
19-OLE reacts with the blood group H type 2 antigens, trisaccharide Fuc1-2Gal1-4GlcNAc1 of human origin. This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Anwendungsbeschreibung:
Immunofluorescence (2-4ug/ml), Immunohistology (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Opt
Formalin-paraffin human Colon Carcinoma stained with Blood Group Antigen H Type 2 MAb (19-OLE)
Formalin-paraffin human Colon Carcinoma stained with Blood Group Antigen H Type 2 MAb (19-OLE)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
