Glycophorin A / CD235a (Erythrocyte Marker) Antibody, IgG1, Clone: [JC159], Mouse, Monoclonal

Artikelnummer: NBT-2993-MSM7-P1ABX
Artikelname: Glycophorin A / CD235a (Erythrocyte Marker) Antibody, IgG1, Clone: [JC159], Mouse, Monoclonal
Artikelnummer: NBT-2993-MSM7-P1ABX
Hersteller Artikelnummer: 2993-MSM7-P1ABX
Alternativnummer: NBT-2993-MSM7-P1ABX-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: FC, IF, IHC
Spezies Reaktivität: Human
Immunogen: Formalin fixed membrane from a Hairy cell leukemia
Alternative Synonym: Blood group--MN locus, GPA, GPErik, GpMiIII, GPSAT, GYPA, MN sialoglycoprotein, MNS, PAS2, Sialoglycoprotein alpha
Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.
Klonalität: Monoclonal
Klon-Bezeichnung: [JC159]
Molekulargewicht: 39kDa
Isotyp: IgG1
NCBI: 2993
UniProt: P02724
Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Anwendungsbeschreibung: Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), ,Immunohistochemistry (Formalin-fixed) (0.25-0.5ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for
Formalin-fixed, paraffin-embedded human Tonsil stained with Glycophorin A Mouse Monoclonal Antibody (JC159).
SDS-PAGE Analysis of Purified Glycophorin A Mouse Monoclonal Antibody (JC159). Confirmation of Integrity and Purity of Antibody.