Recombinant Tenascin C (Stromal Marker for Epithelial Malignancy) Antibody, Clone: [TNC/2981R], Rabbit, Monoclonal

Artikelnummer: NBT-3371-RBM2-P1ABX
Artikelname: Recombinant Tenascin C (Stromal Marker for Epithelial Malignancy) Antibody, Clone: [TNC/2981R], Rabbit, Monoclonal
Artikelnummer: NBT-3371-RBM2-P1ABX
Hersteller Artikelnummer: 3371-RBM2-P1ABX
Alternativnummer: NBT-3371-RBM2-P1ABX-100
Hersteller: NeoBiotechnologies
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Recombinant human full-length TNC protein
Alternative Synonym: Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion (HXB), JI, Myotendinous antigen, Neuronectin, TNC
In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
Klonalität: Monoclonal
Klon-Bezeichnung: [TNC/2981R]
Molekulargewicht: 210kDa and 300kDa
NCBI: 3371
UniProt: P24821
Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Recombinant Monoclonal Antibody
Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes) ,Optimal diluti
Formalin-fixed, paraffin-embedded human Lung Carcinoma stained with Tenascin C Rabbit Recombinant Monoclonal Antibody (TNC/2981R).
SDS-PAGE Analysis of Purified Tenascin C Rabbit Recombinant Monoclonal Antibody (TNC/2981R). Confirmation of Purity and Integrity of Antibody.