Recombinant protein of 321 amino acids representing the N-terminus of the human androgen receptor
Alternative Synonym:
AIS, Dihydrotestosterone receptor (DHTR), HUMARA, HYSP1, Kennedy disease (KD), Nuclear receptor subfamily 3 group C member 4 (NR3C4), SMAX1, Spinal and bulbar muscular atrophy (SBMA), Testicular Feminization (TFM)
Androgen Receptor is a member of the superfamily of ligand responsive transcription regulators. The androgen receptor functions in the nucleus where it is believed to act as a transcriptional regulator mediating the action of male sex hormones. The androgen receptor has wide distribution and can be demonstrated by immunohistochemistry in several tissues including prostate, skin, and oral mucosa. Androgen receptor has been reported in a diverse range of human tumors including osteosarcoma, and in prostatic carcinoma androgen receptor expression may be of clinical relevance.
200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified Androgen Receptor Recombinant Mouse Monoclonal Antibody (r2F12). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human prostate stained with Androgen Receptor Recombinant Mouse Monoclonal Antibody (r2F12). Inset: PBS instead of primary antibody, secondary only negative control.
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