A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human podocalyxin
Alternative Synonym:
PODXL, PDXL, GCTM-2, Gp200, PCLP1, Pcx, Podocalyxin-like protein 1
Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Anwendungsbeschreibung:
Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Immunoprecipitation (1-2ug/500ug protein), Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating
Western Blot Analysis of HeLa cell lysate using Podocalyxin Mouse Monoclonal Antibody (3D3).
Formalin-fixed, paraffin-embedded human Placenta s
Formalin-fixed, paraffin-embedded human Angiosarcoma stained with Podocalyxin Mouse Monoclonal Antibody (3D3).
Western Blot Analysis of HeLa cell lysate using Podocalyxin Mouse Monoclonal Antibody (3D3).
Formalin-fixed, paraffin-embedded human Placenta stained with Podocalyxin Mouse Monoclonal Antibody (3D3).
Confocal Immunofluorescence of HeLa cells using Podocalyxin Mouse Monoclonal Antibody (3D3) labeled with CF488 (Green), Reddot is used to label the nuclei.
Flow Cytometry of NCCIT cells using Podocalyxin Mouse Monoclonal Antibody (3D3).
SDS-PAGE Analysis Purified Podocalyxin Mouse Monoclonal Antibody (3D3). Confirmation of Integrity and Purity of Antibody.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
