Recombinant Transcription factor E3 / TFE3 (Transcription Factor) Antibody, Clone: [TFE3/6849R], Rabbit, Monoclonal

Artikelnummer: NBT-7030-RBM1-P1ABX
Artikelname: Recombinant Transcription factor E3 / TFE3 (Transcription Factor) Antibody, Clone: [TFE3/6849R], Rabbit, Monoclonal
Artikelnummer: NBT-7030-RBM1-P1ABX
Hersteller Artikelnummer: 7030-RBM1-P1ABX
Alternativnummer: NBT-7030-RBM1-P1ABX-100
Hersteller: NeoBiotechnologies
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Recombinant full-length human TFE3 protein
Alternative Synonym: NBLST2, NBPhox, Neuroblastoma paired type homeobox protein, Paired mesoderm homeobox protein 2B, Paired-like homeobox 2B, PHOX2B homeodomain protein, PMX2B
Transcription factor E3 (TFE3) belongs to the basic helix-loop-helix zipper transcription factor family.vC OOThe TFE3 gene is located on the short arm of the X chromosome, is expressed in various cells of the human body, and participates in the regulation of various genes.vC OOThe rearrangement of this gene is associated with a variety of tumors, and it is highly expressed in acinar soft tissue sarcoma with TFE3 fusion gene, Xp11.2 translocation/TFE3 gene fusion-related renal cell carcinoma, and in perivascular epithelioid cell tumors. positive expression.
Klonalität: Monoclonal
Klon-Bezeichnung: [TFE3/6849R]
Molekulargewicht: 62kDa
NCBI: 7030
UniProt: P19532
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Recombinant Monoclonal Antibody
Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),Optimal dilutio
IHC analysis of formalin-fixed, paraffin-embedded human MiT translocation RCC. Nuclear staining using TFE3/6849R at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. 2°,: HRP-polymer, 30min. DAB, 5min.
IHC analysis of formalin-fixed, paraffin-embedded human clear cell RCC. Negative tissue control using TFE3/6849R at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2°,: HRP-polymer, 30min. DAB, 5min.
IHC analysis of formalin-fixed, paraffin-embedded human MiT translocation RCC. Nuclear staining using TFE3/6849R at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. 2°,: HRP-polymer, 30min. DAB, 5min.