It recognizes polypeptides of 58kDa and 56kDa, identified as cytokeratin 5 and 6 respectively. It shows no reaction with keratin 1, 8, or 19. It stains the basal cells of squamous and glandular epithelia, part of stratum spinosum of squamous epithelium, myoepithelium, and mesothelium. It does not stain adenous epithelium. Therefore, this antibody can be used to distinguish squamous carcinoma from adenocarcinoma, and to differentiate epitheliod mesothelioma from non-epitheliod mesothelioma and adenocarcinoma. It is also a useful antibody in the identification of mesothelioma and lung squamous cell carcinoma.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human Basal Cell Carcinoma stained with Cytokeratin 5/6 Mouse Monoclonal Antibody (KRT5.6/2438).
Formalin-fixed, paraffin-embedded human Tonsil stained with Cytokeratin 5/6 Mouse Monoclonal Antibody (KRT5.6/2438).
SDS-PAGE Analysis Purified Cytokeratin 5/6 Mouse Monoclonal Antibody (KRT5.6/2438). Confirmation of Integrity and Purity of Antibody.
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