Recombinant Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) Antibody, IgG1, Clone: [rKRTL/8751], Mouse, Monoclonal
Artikelnummer:
NBT-MSM56-8751-P1ABX
Hersteller Artikelnummer:
MSM56-8751-P1ABX
Alternativnummer:
NBT-MSM56-8751-P1ABX-100
Hersteller:
NeoBiotechnologies
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC, WB
Spezies Reaktivität:
Bovine, Canine, Gallus, Human, Monkey, Mouse, Rabbit, Rat, Reptile
Immunogen:
Human epidermal keratin
Alternative Synonym:
K1B, KRT1B, Keratin, type II cytoskeletal 1b, K77, CK-1B, Keratin 1B, Keratin-77, Cytokeratin-1B, Type-II Keratin Kb39
This MAb recognizes the 56.5kDa (CK10), 50kDa (CK14), 50kDa (CK15), 48kDa (CK16), 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human placenta stained with CK, LMW Recombinant Mouse Monoclonal Antibody (rKRTL/8751). Inset: PBS instead of primary antibody, secondary only negative control.
SDS-PAGE Analysis of Purified CK LMW Recombinant Mouse Monoclonal (rKRTL/8751). Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of Human Skin and A431 lysates using Cytokeratin, Acidic (Type I or LMW) Mouse Recombinant Monoclonal Antibody (rKRTL/8751).
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