Insulin-Like Growth Factor I, Recombinant, Human, aa49-118 (IGF1)
Artikelnummer:
USB-I7661-09J
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| Artikelname: | Insulin-Like Growth Factor I, Recombinant, Human, aa49-118 (IGF1) |
| Artikelnummer: | USB-I7661-09J |
| Hersteller Artikelnummer: | I7661-09J |
| Alternativnummer: | USB-I7661-09J-100,USB-I7661-09J-500 |
| Hersteller: | US Biological |
| Kategorie: | Molekularbiologie |
| The Insulin-like growth factor-1 (IGF-1) is mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF-1 is predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGF-1 belongs to the insulin gene family, which also contains insulin and relaxin. The IGF-1 is similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. This recombinant human IGF-I is globular protein containing 71 amino acids, and 3 intra-molecular disulfide bonds. Recombinant protein corresponding to aa49-118 from human IGF1, expressed in E. coli. Accession: NP_000609.1 Biological Activity: Measured in a cell proliferation assay using MCF-7 human breast cancer cells. The ED50 range is 5ng/ml Amino Acid Sequence: MGPETLCGAE LVDALQFVCG DRGFYFNKPT GYGSSSRRAP QTGIVDECCF RSCDLRRLEM YCAPLKPAKS A Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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