IRAK 3, NT (Interleukin-1 Receptor-associated Kinase 3, IRAK3, IRAK-3, ASRT5, FLJ13601, IL-1 Receptor-associated Kinase M, IRAKM, IRAK-M) (Biotin), Rabbit
Artikelnummer:
USB-I8600-16N-BIOTIN
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| Artikelname: | IRAK 3, NT (Interleukin-1 Receptor-associated Kinase 3, IRAK3, IRAK-3, ASRT5, FLJ13601, IL-1 Receptor-associated Kinase M, IRAKM, IRAK-M) (Biotin), Rabbit |
| Artikelnummer: | USB-I8600-16N-BIOTIN |
| Hersteller Artikelnummer: | I8600-16N-Biotin |
| Alternativnummer: | USB-I8600-16N-BIOTIN-200 |
| Hersteller: | US Biological |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Immunogen: | KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 45-77 in the N-terminal region of human IRAK 3, Swiss/UniProt Accession: Q9Y616. |
| Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody. |
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