Sialoprotein, Bone (BSP, Bone Sialoprotein 2, BSP2, Cell-binding Sialoprotein, Integrin-binding Sialoprotein), Gallus
Artikelnummer:
USB-S1013-34M
Hersteller Artikelnummer:
S1013-34M
Alternativnummer:
USB-S1013-34M-10,USB-S1013-34M-100
Hersteller:
US Biological
Wirt:
Gallus
Kategorie:
Antikörper
Applikation:
ELISA, FC, IHC, RIA, WB
Immunogen:
Human Bone Sialoprotein (bone extract)
Bone sialoprotein (BSP) is one of the major noncollagenous proteins in the extracellular matrix of bone. It is a phosphorylated glycoprotein with an approximate molecular weight of 70-80kD. The protein has been found in osteoblasts and osteocytes. BSP is synthesized and secreted by bone-, dentin- and cementum-forming cells. Diseases concerning the bone turnover, pathological bone alterations as well as the rapid increase of osteoporosis make it necessary to establish new markers. Bone sialoprotein is discussed as a potential serum marker for monitoring bone remodelling. Applications: Suitable for use in ELISA, Western Blot, RIA, Immunohistochemistry and Flow Cytometry. Other applications not tested. Recommended Dilutions: ELISA: 1ug/ml Western Blot: 1:100 Immunohistochemistry (Paraffin): 4ug/ml RIA: 20ng/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.