Talin (TLN, Talin 1, Talin-1, TLN1, ILWEQ, KIAA1027), IgG1, Clone: [97H6], Mouse, Monoclonal
Artikelnummer:
USB-T0750-02A
Hersteller Artikelnummer:
T0750-02A
Alternativnummer:
USB-T0750-02A-100,USB-T0750-02A-200
Hersteller:
US Biological
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IF, IHC, IP, WB
Immunogen:
Human Talin-1
Talin-1 is a high molecular weight cytoskeletal protein, linking vinculin to the integrins, thereby linking the cytoskeleton to the extracellular matrix. It is specifically found in regions of cell-substratum contact and in lymphocytes at cell-cell contact points. Talin-1 plays a role in the assembly of actin filaments and in the migration of cells such as osteoclasts and fibroblasts. Applications: Suitable for use in Immunohistochemistry, Immunoprecipitation, Immunofluorescence and Western Blot. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry (paraffin): 1:125-1:200 Requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Immunofluorescence: Requires fixation and permeabilization using methanol. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
