TEX19.1 (Testis-expressed Protein 19.1, Testis-expressed Protein 19A, Testis-expressed Sequence 19A, Tex19, Tex19a), IgG2a, Clone: [11n188], Rat, Monoclonal
Artikelnummer:
USB-T3543-40
Hersteller Artikelnummer:
T3543-40
Alternativnummer:
USB-T3543-40-100
Hersteller:
US Biological
Wirt:
Rat
Kategorie:
Antikörper
Immunogen:
Recombinant corresponding to aa189-351 from mouse TEX19.1 expressed in E. coli.
Testis-expressed protein 19.1 is a 40kD pluripotent stem cell molecule. Mouse TEX19.1 is 351aa in length. The first conserved domain is localized on the N-terminal boundary of the protein and is 58 residues long. It is known as the MCP domain, and begins with an invariant MCPPVS motif. The second conserved domain, known as the VPTEL domain, begins with an invariant VPTEL motif and is 38aa long. Mouse TEX19.1 shares 70-24aa identity with rat and human Tex19.1, respectively. The protein is restricted to mammals and is expressed in testis, placenta, and ovary. It is expressed in early embryo and is later limited to the germ line. Tex19.1 has been shown to present in the cytoplasm of spermatogonia and early spermatocytes in adult mouse testes (1). The precise function of TEX19.1 is still unknown, but it is thought to be a new transcription factor regulating target genes responsible for pluripotency or it has a role in controlling the chromatin architecture of the pluripotent nucleus. Applications: Suitable for use in Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunocytochemistry: 8-25ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
