TIMP2 (Metalloproteinase Inhibitor 2, CSC-21K, Tissue Inhibitor of Metalloproteinases 2, TIMP-2), Clone: [3A4], Mouse, Monoclonal
Artikelnummer:
USB-T5585-25A
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| Artikelname: | TIMP2 (Metalloproteinase Inhibitor 2, CSC-21K, Tissue Inhibitor of Metalloproteinases 2, TIMP-2), Clone: [3A4], Mouse, Monoclonal |
| Artikelnummer: | USB-T5585-25A |
| Hersteller Artikelnummer: | T5585-25A |
| Alternativnummer: | USB-T5585-25A-100 |
| Hersteller: | US Biological |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | ELISA, FC, IF, IHC, WB |
| Immunogen: | Protein corrresponding to aa56-66 (DSGNDIYGNPI) from human TIMP2. |
| TIMP-2 is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kD Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kD Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 innibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. Applications: Suitable for use in ELISA, Flow Cytometry, Immunofluorescence, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT. Requires HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min. Flow Cytometry: 0.5-1ug/10e6 cells Western Blot: 1-2ug/ml Immunofluorescence: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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