Tissue Inhibitor of Metalloproteinases 2 (TIMP2) (BSA and Azide Free), Clone: [2Q762 67-4H11], Mouse, Monoclonal
Artikelnummer:
USB-T5585-27X
Hersteller Artikelnummer:
T5585-27X
Alternativnummer:
USB-T5585-27X-100
Hersteller:
US Biological
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
ELISA, IHC, WB
Immunogen:
Synthetic peptide corresponding to aa178-193, YRGAAPPKQEFLDIED of human TIMP-2.
TIMP-2 is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kD Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kD Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. Applications: Suitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: 5ug/ml (PLP fixed tissue), 1ug/ml (Frozen tissues) Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.