Urodilatin (Atrial Natriuretic Peptide) (Not for Export EU), Sheep
Artikelnummer:
USB-U1750-01B
Hersteller Artikelnummer:
U1750-01B
Alternativnummer:
USB-U1750-01B-20, USB-U1750-01B-100
Hersteller:
US Biological
Wirt:
Sheep
Kategorie:
Antikörper
Applikation:
RIA
Immunogen:
Synthetic peptide corresponding to aa95-101, TAPRSLR-ßAC from human Urodilatin comjugated to KLH
Urodilatin is a natriuretic peptide isolated from human urine and belongs to the family of A type natriuretic peptides. Urodilatin is differentially processed to a peptide of 32aa from the same precursor as ANP. It is synthesized in kidney tubular cells and secreted luminally. After secretion from epithelial cells of the distal and/or connecting tubules, Urodilatin interacts downstream at distal segments of the nephron with luminally located receptors whereby it regulates Na(+) and water reabsorption. Thus, the physiological function of the renal Urodilatin system can be described as a paracrine intrarenal regulator for Na(+) and water homeostasis, considering Urodilatin as a real diuretic natriuretic regulatory peptide. Applications: Suitable for use in RIA. Other applications not tested. Recommended Dilutions: RIA: 1:240,000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
