CBFA2T3 Rabbit pAb, Unconjugated, Polyclonal

Catalog Number: ABB-A14712
Article Name: CBFA2T3 Rabbit pAb, Unconjugated, Polyclonal
Biozol Catalog Number: ABB-A14712
Supplier Catalog Number: A14712
Alternative Catalog Number: ABB-A14712-20UL,ABB-A14712-100UL,ABB-A14712-1000UL,ABB-A14712-500UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: ETO2, MTG16, MTGR2, ZMYND4, RUNX1T3, CBFA2T3
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16,21)(q24,q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5-region of the runt-related transcription factor 1 gene fused to the 3-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
Clonality: Polyclonal
Molecular Weight: 71kDa
NCBI: 863
UniProt: O75081
Purity: Affinity purification
Sequence: GQSLQGPTAVVADPVPGPPEAAHSLGPSLPVGAASPSEAGSAGPSRPGSPSPPGPLDTVPR
Target: CBFA2T3
Antibody Type: Primary Antibody
Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors. Shipping: Ice Bag
Western blot analysis of various lysates using CBFA2T3 Rabbit pAb (A14712) at 1:900 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates / proteins: 25 µg per lane.
Blocking buffer: 3 % nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time:90s.