p70 S6 Kinase 2 Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A1541
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| Article Name: | p70 S6 Kinase 2 Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A1541 |
| Supplier Catalog Number: | A1541 |
| Alternative Catalog Number: | ABB-A1541-20UL,ABB-A1541-100UL,ABB-A1541-1000UL,ABB-A1541-500UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | KLS, SRK, S6K2, S6KB, STK14B, S6KI(2), S6Kbeta, p70S6Kb, P70-beta, S6K-beta2, P70-beta-1, P70-beta-2, p70(S6K)-beta, p70 S6 Kinase 2 |
| This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. |
| Clonality: | Polyclonal |
| Molecular Weight: | 53kDa |
| NCBI: | 6199 |
| UniProt: | Q9UBS0 |
| Purity: | Affinity purification |
| Sequence: | MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDT |
| Target: | RPS6KB2 |
| Antibody Type: | Primary Antibody |
| Application Dilute: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,Kinase,Serine threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,TGF-b-Smad Signaling Pathway,Endocrine Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Obesity,Immunology Inflammation,B Cell Receptor Signaling Pathway,Cardiovascular,Angiogenesis. Shipping: Ice Bag |
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Western blot analysis of various lysates using p70 S6 Kinase 2 Rabbit pAb (A1541) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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