Muscarinic AChR M2 (ACM2) Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A1567
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| Article Name: | Muscarinic AChR M2 (ACM2) Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A1567 |
| Supplier Catalog Number: | A1567 |
| Alternative Catalog Number: | ABB-A1567-20UL,ABB-A1567-100UL,ABB-A1567-1000UL,ABB-A1567-500UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | HM2, Muscarinic AChR M2 (ACM2) |
| The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. |
| Clonality: | Polyclonal |
| Molecular Weight: | 52kDa |
| NCBI: | 1129 |
| UniProt: | P08172 |
| Purity: | Affinity purification |
| Sequence: | HISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRT |
| Target: | CHRM2 |
| Antibody Type: | Primary Antibody |
| Application Dilute: | WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human. ResearchArea: Signal Transduction,G protein signaling,G-Protein-Coupled ReceptorsGPCR,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease. Shipping: Ice Bag |
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Western blot analysis of various lysates using Muscarinic AChR M2 (ACM2) Rabbit pAb (A1567) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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