D2HGDH Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A16213
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| Article Name: | D2HGDH Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A16213 |
| Supplier Catalog Number: | A16213 |
| Alternative Catalog Number: | ABB-A16213-100UL,ABB-A16213-20UL,ABB-A16213-1000UL,ABB-A16213-500UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | D2HGD, D2HGDH |
| This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features. |
| Clonality: | Polyclonal |
| Molecular Weight: | 56kDa |
| NCBI: | 728294 |
| UniProt: | Q8N465 |
| Purity: | Affinity purification |
| Sequence: | GRHLHLASPVQESPFYVLIETSGSNAGHDAEKLGHFLEHALGSGLVTDGTMATDQRKVKMLWALRERITEALSRDGYVYKYDLSLPVERLYDIVTDLRARLGPHAKHVVGYGHLGDGNLHLNVTAEAFSPSLLAALEPHVYEWTAGQQGSVSAEHGVGFRKRDVLGYSKPPGALQLMQQLKALLDPKGILNPYKTLPSQA |
| Target: | D2HGDH |
| Antibody Type: | Primary Antibody |
| Application Dilute: | WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Mouse,Rat. ResearchArea: Endocrine Metabolism. Shipping: Ice Bag |
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Western blot analysis of various lysates using D2HGDH Rabbit pAb (A16213) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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