KCNA4 Rabbit pAb, Unconjugated, Polyclonal

Catalog Number: ABB-A16390
Article Name: KCNA4 Rabbit pAb, Unconjugated, Polyclonal
Biozol Catalog Number: ABB-A16390
Supplier Catalog Number: A16390
Alternative Catalog Number: ABB-A16390-20UL,ABB-A16390-100UL,ABB-A16390-1000UL,ABB-A16390-500UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: HK1, HBK4, PCN2, HPCN2, HUKII, KCNA8, KV1.4, KCNA4L, MCIDDS, KCNA4
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.
Clonality: Polyclonal
Molecular Weight: 73kDa
NCBI: 3739
UniProt: P22459
Purity: Affinity purification
Sequence: DIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGL
Target: KCNA4
Antibody Type: Primary Antibody
Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Mouse,Rat. ResearchArea: Neuroscience. Shipping: Ice Bag
Western blot analysis of lysates from Rat brain, using KCNA4 Rabbit pAb (A16390) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 20s.