H2-Aa Rabbit pAb, Polyclonal
Catalog Number:
ABB-A18325
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| Article Name: | H2-Aa Rabbit pAb, Polyclonal |
| Biozol Catalog Number: | ABB-A18325 |
| Supplier Catalog Number: | A18325 |
| Alternative Catalog Number: | ABB-A18325-20UL,ABB-A18325-100UL,ABB-A18325-1000UL,ABB-A18325-500UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Alternative Names: | Ia1, H2Aa, Ia-1, H-2Aa, Aalpha, IAalpha, I-Aalpha, H2-Aa |
| Enables peptide antigen binding activity. Involved in response to interferon-gamma. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and positive regulation of T cell differentiation. Located in external side of plasma membrane and lysosome. Part of MHC class II protein complex. Is expressed in central nervous system, retina, and thymus primordium. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple), gastrointestinal system cancer (multiple), glomerulonephritis (multiple), hematologic cancer (multiple), and systemic scleroderma (multiple). Orthologous to several human genes including HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1). |
| Clonality: | Polyclonal |
| Molecular Weight: | 28kDa |
| NCBI: | 14960 |
| UniProt: | P14434 |
| Purity: | Affinity purification |
| Sequence: | IEADHVGTYGISVYQSPGDIGQYTFEFDGDELFYVDLDKKETVWMLPEFGQLASFDPQGGLQNIAVVKHNLGVLTKRSNSTPATNEAPQATVFPKSPVLLGQPNTLICFVDNIFPPVINITWLRNSKSVADGVYETSFFVNRDYSFHKLSYLTFIPSDDDIYDCKVEHWGLEEPVLKHWEPE |
| Target: | H2-Aa |
| Antibody Type: | Primary Antibody |
| Application Dilute: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human,Mouse. Shipping: Ice Bag |
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Western blot analysis of various lysates using H2-Aa Rabbit pAb (A18325) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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