Papillary renal cell carcinoma Rabbit pAb, Unconjugated, Polyclonal

Catalog Number: ABB-A18781
Article Name: Papillary renal cell carcinoma Rabbit pAb, Unconjugated, Polyclonal
Biozol Catalog Number: ABB-A18781
Supplier Catalog Number: A18781
Alternative Catalog Number: ABB-A18781-100UL,ABB-A18781-20UL,ABB-A18781-1000UL,ABB-A18781-500UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: TPRC, RCCP1, Papillary renal cell carcinoma
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X,1)(p11,q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.
Clonality: Polyclonal
Molecular Weight: 52kDa
NCBI: 5546
UniProt: Q92733
Purity: Affinity purification
Sequence: PSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDANAAGAYYQDYYSGGYYPAQDPALVPPQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWSENKLSRRQTQAKYGF
Target: PRCC
Antibody Type: Primary Antibody
Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Human. ResearchArea: Cancer,Tumor immunology,Tumor-associated antigens,Immunology Inflammation. Shipping: Ice Bag
Western blot analysis of lysates from HeLa cells, using Papillary renal cell carcinoma Rabbit pAb (A18781) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit (RM00021).
Exposure time: 180s.