CXCR4 Rabbit mAb, Unconjugated, Monoclonal
Catalog Number:
ABB-A19035
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| Article Name: | CXCR4 Rabbit mAb, Unconjugated, Monoclonal |
| Biozol Catalog Number: | ABB-A19035 |
| Supplier Catalog Number: | A19035 |
| Alternative Catalog Number: | ABB-A19035-100UL,ABB-A19035-20UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | FB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LAP-3, LESTR, NPY3R, NPYRL, WHIMS, HSY3RR, NPYY3R, WHIMS1, D2S201E, CXCR4 |
| This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Application Dilute: | WB,1:1000 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human. ResearchArea: Cancer,Signal transduction,G protein signaling,G-Protein-Coupled receptors,GPCR,ErbB-HER signaling pathway,Cell biology developmental biology,Apoptosis,Endocrine metabolism,Immunology Inflammation,CDs,Cell Intrinsic Innate Immunity signaling pathway,Neuroscience,Stem cells,Hematopoietic progenitors,Neural stem cells,Cardiovascular,Angiogenesis. Shipping: Ice Bag |
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Western blot analysis of lysates from HeLa cells, using CXCR4 Rabbit mAb (A19035) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min. |
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