PAI-1/Serpin E1 Rabbit mAb, Unconjugated, Monoclonal

Catalog Number: ABB-A19096
Article Name: PAI-1/Serpin E1 Rabbit mAb, Unconjugated, Monoclonal
Biozol Catalog Number: ABB-A19096
Supplier Catalog Number: A19096
Alternative Catalog Number: ABB-A19096-20UL,ABB-A19096-100UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: PAI, PAI1, PAI-1, PLANH1, PAI-1/Serpin E1
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.
Clonality: Monoclonal
Molecular Weight: 45kDa
NCBI: 5054
UniProt: P05121
Purity: Affinity purification
Target: SERPINE1
Application Dilute: WB,1:1000 - 1:4000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Human,Monkey. ResearchArea: Cancer,Tumor biomarkers,Signal Transduction,Cell Biology Developmental Biology,Ubiquitin,Endocrine Metabolism,Endocrine and metabolic diseases,Cardiovascular,Angiogenesis,Blood. Shipping: Ice Bag
Western blot analysis of various lysates using PAI-1/Serpin E1 Rabbit mAb (A19096) at 1:1000 dilution incubated overnight at 4°C.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 45s.