beta glucuronidase (GUSB) Rabbit mAb, Unconjugated, Monoclonal

Catalog Number: ABB-A19248
Article Name: beta glucuronidase (GUSB) Rabbit mAb, Unconjugated, Monoclonal
Biozol Catalog Number: ABB-A19248
Supplier Catalog Number: A19248
Alternative Catalog Number: ABB-A19248-100UL,ABB-A19248-20UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: BG, MPS7, beta glucuronidase (GUSB)
This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.
Clonality: Monoclonal
Molecular Weight: 75kDa
NCBI: 2990
UniProt: P08236
Purity: Affinity purification
Target: GUSB
Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Human. ResearchArea: Cancer,Signal Transduction,Endocrine Metabolism,Lipid Metabolism. Shipping: Ice Bag
Western blot analysis of various lysates using beta glucuronidase (GUSB) Rabbit mAb (A19248) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180s.