ANPRB/NPR2 Rabbit mAb, Unconjugated, Monoclonal
Catalog Number:
ABB-A19255
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| Article Name: | ANPRB/NPR2 Rabbit mAb, Unconjugated, Monoclonal |
| Biozol Catalog Number: | ABB-A19255 |
| Supplier Catalog Number: | A19255 |
| Alternative Catalog Number: | ABB-A19255-100UL,ABB-A19255-20UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | GCB, AMD1, AMDM, ANPb, ECDM, GC-B, NPRB, SNSK, ANPRB, GUC2B, NPRBi, GUCY2B, ANPRB/NRP2 |
| This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. |
| Application Dilute: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Mouse. ResearchArea: Signal Transduction,G protein signaling,G-Protein-Coupled ReceptorsGPCR,Neuroscience,Cardiovascular,Blood. Shipping: Ice Bag |
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Western blot analysis of various lysates using ANPRB/NPR2 Rabbit mAb (A19255) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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