PGC1alpha/beta Rabbit mAb, Unconjugated, Monoclonal

Catalog Number: ABB-A19674
Article Name: PGC1alpha/beta Rabbit mAb, Unconjugated, Monoclonal
Biozol Catalog Number: ABB-A19674
Supplier Catalog Number: A19674
Alternative Catalog Number: ABB-A19674-100UL,ABB-A19674-20UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: LEM6, PGC-1(alpha), PGC-1alpha, PGC-1v, PGC1, PGC1A, PPARGC1, ERRL1, PERC, PGC-1(beta), PGC1B, PGC1alpha/beta
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Clonality: Monoclonal
Molecular Weight: 113kDa
NCBI: 10891
UniProt: Q9UBK2
Purity: Affinity purification
Target: PGC1alpha/beta
Application Dilute: WB,1:1000 - 1:6000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Mouse,Rat. Shipping: Ice Bag
Western blot analysis of various lysates using PGC1alpha/beta Rabbit mAb (A19674) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 1s.