Chemical compounds corresponding to 2-O-Methylguanosine(Gm).
Conjugation:
Unconjugated
Alternative Names:
2-O-Methylguanosine, Gm, 2-O-Methylguanosine(Gm)
RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade. 2-O-methyladenosine (Am), 2-O-methylguanosine (Gm),2-O-methylcytidine (Cm),2-O-methyluridine (Um),N 6-methyladenosine (m6A), N 1-methylguanosine (m1G),5-methylcytidine (m5C),and 5-methyluridine (m5U) are representative 2-O-methylation and base-methylation modified epigenetic marks of RNA. 2-O-methyltransferase is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2-O-methylguanosine is thought to stabilize the structure of the tRNA.
DB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes:
Cross-Reactivity: Species independent. ResearchArea: 2-O-methylguanosine is guanosine with the hydrogen on the hydroxyl at position C-2 substituted with a methyl group. It has a role as a metabolite. Shipping: Ice Bag
The 2-O-methylguanosine(Gm) Rabbit mAb (A20696) are tested in Dot Blot against 2-O-methylguanosine and unmodified guanosine.2-O-methylguanosine:Biotin-5GCATAATGACTACT(Gm)3unmodified guanosine:Biotin-5GCATAATGACTACTG3
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