SPINK5 / LEKTI Rabbit mAb, Unconjugated, Monoclonal
Catalog Number:
ABB-A20916
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| Article Name: | SPINK5 / LEKTI Rabbit mAb, Unconjugated, Monoclonal |
| Biozol Catalog Number: | ABB-A20916 |
| Supplier Catalog Number: | A20916 |
| Alternative Catalog Number: | ABB-A20916-20UL,ABB-A20916-100UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | NS, NETS, LEKTI, LETKI, VAKTI, SPINK5 / LEKTI |
| This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants. |
| Application Dilute: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Cell Biology Developmental Biology,Ubiquitin,Cardiovascular,Angiogenesis. Shipping: Ice Bag |
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Western blot analysis of various lysates using SPINK5 / LEKTI Rabbit mAb (A20916) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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