CXCL10/IP-10 Rabbit mAb, Unconjugated, Monoclonal
Catalog Number:
ABB-A21986
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| Article Name: | CXCL10/IP-10 Rabbit mAb, Unconjugated, Monoclonal |
| Biozol Catalog Number: | ABB-A21986 |
| Supplier Catalog Number: | A21986 |
| Alternative Catalog Number: | ABB-A21986-100UL,ABB-A21986-20UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | C7, IFI10, INP10, IP-10, crg-2, mob-1, SCYB10, gIP-10, CXCL10/IP-10 |
| This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the cytokine storm immune response to SARS-CoV-2 infection. |
| Application Dilute: | WB,1:1000 - 1:10000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human. ResearchArea: Cancer,Invasion and Metastasis,Cell Biology Developmental Biology,Growth factors,Immunology Inflammation,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Angiogenesis. Shipping: Ice Bag |
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Western blot analysis of lysates from THP-1 cells using CXCL10/IP-10 Rabbit mAb (A21986) at 1:1000 dilutionincubated overnight at 4°C. THP-1 cells were treated with IFN-gamma (100 ng/mL), LPS (1 µg/mL) and Brefeldin A (300 ng/mL) for 8 hours. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 30 µg per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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